Endocrine Abstracts

Background and study aims: Increased aldosterone production in the adrenal gland plays a role in many hypertensive patients. Structural changes of the zona glomerulosa with age in normotensive patients have been described in literature but the influence of aging on aldosterone secretion and physiology is unclear. The aim of this study is to investigate changes in the ZG in order to gain insight in the origin, development and definition of aldosterone producing cell clusters (A...